Some people will swear by a large, central chunk of raid frames. I don’t for example, but find TinyTip very useful. Most of the information you need can be gathered by this and just your eyes I reckon. With Tinytip I can quickly scan over every unit in a middle of complicated fight and figure out who needs healing and in what order.

Some people like to combine this with mouseover healing – but for me that doesn’t feel too comfortable, I still like to manually select targets with a click.